the effect of l-carnitine on sperm parameters in patients candidated for intracytoplasmic sperm injection
نویسندگان
چکیده
background: the etiologic cause in near one third of male factor infertility is unknown. the percentage of men with idiopathic infertility who have been successfully treated by the empirical therapeutic modalities is not high. objective: the aim of this study was to assay the effect of l-carnitine on sperm parameters in patients who needs intracytoplasmic sperm injection (icsi) as a method for infertility treatment. materials and methods: the study population consisted of 65 men (mean age± sd: 34.4 ± 6.07) presenting with primary infertility due to idiopathic oligoasthenoteratozoospermia. l-carnitine was prescribed 1gram orally every 8 hours for 3 months. before and after the ending of the l-carnitine treatment, semen analysis was performed. results: the proportion of patients who had motile and grade c sperms rose significantly after treatment. percentile of abnormal shaped sperms decreased significantly after treatment. in approximately 22%, complete asthenozoospermia changed to relative asthenozoospermia. conclusion: appearing motile sperms will potentially improve the technique of icsi. the magnitude of the elevation in normal morphology is not clinically obvious, but it seems that it can be important in obtaining normal-shaped sperms for intracytoplasmic injection. designing a study on selected patients with complete asthenozoospermia who have not other abnormalities in semen parameters can reveal the real effect of carnitine therapy in this category. article
منابع مشابه
The effect of L-carnitine on sperm parameters in patients candidated for Intracytoplasmic Sperm Injection
Background: The etiologic cause in near one third of male factor infertility is unknown. The percentage of men with idiopathic infertility who have been successfully treated by the empirical therapeutic modalities is not high. Objective: The aim of this study was to assay the effect of L-carnitine on sperm parameters in patients who needs intracytoplasmic sperm injection (ICSI) as a method for ...
متن کاملIntracytoplasmic Sperm Injection
Intracytoplasmic Sperm Injection (ICSI) is an assisted reproductive technique [4] (ART) initially developed by Dr. Gianpiero D. Palermo [5] in 1993 to treat male infertility [6]. It is most commonly used in conjunction with in vitro [7] fertilization [8] (IVF) or a less commonly used technique called zygote intrafallopian transfer [9] (ZIFT). In natural fertilization [8], the sperm [10] must pe...
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OBJECTIVE The aim of this study was to evaluate the efficiency of the intracytoplasmic morphologically selected sperm injection (IMSI) technique compared with conventional ICSI and previous ICSI attempts in oligo-astheno-teratozoospermia (OAT) patients. METHODS The sperms were selected under high magnification (6,600×) and used to induce fertilization in previous ICSI patients by IMSI. These ...
متن کاملIntracytoplasmic sperm injection (ICSI)
IVF has become a well-established treatment for certain types of infertility, including long-standing infertility due to tubal disease, endometriosis, unexplained infertility or infertility involving a male factor. Soon it became clear that certain couples with severe male-factor infertility could not be helped by conventional IVF. Extremely low sperm counts, impaired motility and/or abnormal m...
متن کاملIndications for intracytoplasmic sperm injection.
Intracytoplasmic sperm injection (ICSI) is the latest of several microfertilization techniques that have been utilized predominantly to overcome severe male subfertility, giving fertilization and term pregnancy rates similar to conventional in-vitro fertilization (IVF) (but for other indications). Even though available data on children born after ICSI are very encouraging, the procedure must st...
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عنوان ژورنال:
international journal of reproductive biomedicineجلد ۲، شماره ۲، صفحات ۶۵-۰
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